Search results for "function prediction"
showing 6 items of 6 documents
Exploration of Evolutionary Relations between Protein Structures
2008
We describe a new method for the exploration of evolutionary relations between protein structures.
Extracting similar sub-graphs across PPI Networks
2009
Singling out conserved modules (corresponding to connected sub-graphs) throughout protein-protein interaction networks of different organisms is a main issue in bioinformatics because of its potential applications in biology. This paper presents a method to discover highly matching sub-graphs in such networks. Sub-graph extraction is carried out by taking into account, on the one side, both protein sequence and network structure similarities and, on the other side, both quantitative and reliability information possibly available about interactions. The method is conceived as a generalization of a known technique, able to discover functional orthologs in interaction networks. Some preliminar…
Comparing various concepts of function prediction. Part 2.
1975
Prediction: f(m+1) is guessed from given f(0), ..., f(m). Program synthesis: a program computing f is guessed from given f(0), ..., f(m). The hypotheses are required to be correct for all sufficiently large m, or with some positive frequency. These approaches yield a hierarchy of function prediction and program synthesis concepts. The comparison problem of the concepts is solved.
Comparing various concepts of function prediction. Part 1.
1974
Prediction: f(m+1) is guessed from given f(0), ..., f(m). Program synthesis: a program computing f is guessed from given f(0), ..., f(m). The hypotheses are required to be correct for all sufficiently large m, or with some positive frequency. These approaches yield a hierarchy of function prediction and program synthesis concepts. The comparison problem of the concepts is solved.
On speeding up synthesis and prediction of functions
1974
Computational complexity of prediction strategies
1977
The value f(m+1) is predicted from given f(1), ..., f(m). For every enumeration T(n, x) there is a strategy that predicts the n-th function of T making no more than log2(n) errors (Barzdins-Freivalds). It is proved in the paper that such "optimal" strategies require 2^2^cm time to compute the m-th prediction (^ stands for expoentiation).